Anti-angiogenic is defined in the American Heritage Dictionary as “of or relating
to a naturally occurring substance, drug, or other compound that can destroy
or interfere with the fine network of blood vessels needed by tumors to
grow and metastasize.”
Beta-cryptoxanthin - carotenoid pigment in orange, red and yellow foods, related to beta-carotene,
ultimately metabolized to vitamin A. Winter squash, pumpkin, persimmons,
papaya, tangerines, red peppers, corn, oranges and apricots
Beta-carotene - sweet potato, carrots, kale, butternut squash, turnip greens, pumpkin,
mustard greens, cantaloupe, sweet red pepper, apricots and spinach
Curcumin - antiangiogenic. Turmeric
Ellagitannins - pomegranate, strawberries, blackberries, raspberries, muscadine grapes,
walnuts, pecans. Pomegranate juice best made from the whole fruit, not
just the arils.
Flavonoids in fruits and vegetables: for the plants, they serve as anti-microbials,
deterrents against those who would eat them, attractants to pollinators
and those who disperse their seeds. Flavonoids in fruits and vegetables
include quercetin, anthocyanidins, proanthocyanidins, ellagitannins.
Spinach, Onions (esp red onion), Parsley, Beets, Thyme, lettuce, chicory,
arugula, red lettuce.
Anthocyanins are pigments that are present in many types of berries and grapes as well
as red wine. They inhibit tumor growth and angiogenesis. They exhibit
a purple color at neutral pH, red in acidic, and blue in alkaline conditions.
Black raspberries, blackberries, strawberries
Proanthocyanidins - a type of tannin found in cacao, cinnamon, cranberry, apples, grapes,
black current, chokeberry, and persimmon. Inhibits ACE activity, lowers CRP.
Cacao (after fermentation), cinnamon, cranberry, black currants, grapes,
chokeberries (very astringent), blueberries, raspberries, strawberries,
bilberries, apples, apple juice (cloudy ones), cinnamon.
Menaquinone (vitamin K2), found in certain food sources is antiangiogenic - cheese
especially. "Menaquinone is distinct from the phylloquinone (Vitamin
K1) present in dark leafy vegetables. Instead, menaquinone is a fat-soluble
vitamin formed naturally by bacteria in fermented dairy products, including
cheese and yogurt, in fermented soy such as natto, and also present in
dark meat. Certain cheeses, such as Dutch Gouda, Swiss Emmental, and Norwegian
Jarlsberg, have particularly high concentrations of menaquinone."
Fermented foods such as cheese, sauerkraut, miso and natto, and animal
foods, especially organ meat and pastured dairy products. The richest
source of menaquinones known is natto.
Other anti-angiogenic foods - Chinese cabbage, citrus fruits (naringenin, hesperidin), silymarin (milk
thistle, artichokes), garlic (diallyl sulfide)